Category Archives: Internal Diseases of Cats

Paracetomol poison to cats

Don’t be tempted to medicate your off-colour cat with paracetamol this holiday season. Paracetamol at any dose is deadly to cats.

Soon after ingesting it cats’ red blood cells lose the ability to carry oxygen. The cats’ gums turn brown, they drool and they become weak and wobbly.

If they survive the first 12-24 hours the liver starts to close down, too. They go off their food, their face, lips and paws swell, their gums and eyes go yellow and their belly swells.

Most cats who ingest paracetamol die unless treated within the first couple of hours.

Aspirin is equally dangerous but more subtle in its effects. Aspirin damages cats’ kidneys and irritates their stomachs.

Very few pain medications are safe for cats. Only give medications prescribed by your vet for your particular puss.

Kidney failure in cats

Mittens getting the right balance

What do kidneys do?

 

The kidneys remove waste products from the blood stream, regulate fluid and electrolyte balance, maintain the acid-base balance of the body and remove toxins and drugs. They also help maintain blood pressure and stimulate blood cell production.

What happens when my cat’s kidneys fail?

Signs of kidney failure don’t appear until at least 70% of kidney function is lost. Chronic kidney failure is known as renal failure.

Kidney damage accumulates for years before we see any signs. Even then the early signs of kidney failure – increased thirst and urine production – are not easily recognised in our feline friends.

You may notice an increasingly wet litter tray if your cat is only indoors. However if you have other cats you may not pick up increased urine production in a single cat.

Cats often drink from multiple water sources making it difficult to recognise increased consumption.

Other signs of kidney failure such as weight loss and poor coat quality are often put down to normal ageing.

Often the first thing we see is a cat off her food, vomiting, depressed and dehydrated. The kidneys are already badly affected by this stage.

How do we diagnose kidney failure?

We diagnose and stage kidney failure with blood tests for the two waste products, urea and creatinine and a urine analysis to measure the kidneys ability to concentrate urine. We also  check the urine for protein loss or a urinary tract infection.

Tests for other substances like potassium, phosphorus and calcium as well as blood cell counts help us decide on the best course of treatment.

Could it have been diagnosed earlier?

Because signs of kidney failure and rises in blood urea and creatinine are not evident until significant loss of kidney function has occurred early diagnosis is difficult. However, we strongly recommend at least annual blood and urine tests, as well as regular body weight checks. If urine concentrating ability is deteriorating or the creatinine is trending up we are able to slow down the progression of the disease with a special kidney protective diet. Any weight loss in a cat should be fully investigated.

What treatments are available?

After initial hospitalisation to treat dehydration and electrolyte disturbances, most cats are managed with a diet change and one or two other medications.

  • Low protein and phosphorus diets lower the level of waste products in the bloodstream.  Try a few of the ready made kidney diets like Royal Canin renal or Hills k/d to find one your cat likes. Once your cat accepts the diet it must be her sole source of nutrition. Although if renal failure is advanced and your cat’s appetite is poor, any diet that the cat enjoys is acceptable.
  • If blood phosphorus levels remain above normal after a few weeks on the special diet we add phosphate binders like Ipakitine to the food. Reducing blood phosphorus makes your cat feel better and slows progression of the disease.
  • Urinary tract infections are common in kidney failure and are treated with antibiotics.
  • Cats with renal failure lose potassium in the urine leading to muscle weakness, stiffness, a poor coat and exacerbation of the kidney failure. The special kidney diets contain extra potassium but sometimes we have to add more.
  • Severely affected cats need extra fluids. We can teach you to administer      subcutaneous fluids at home to reduce dehydration in advanced cases.

FRESH WATER MUST BE AVAILABLE AT ALL TIMES

How long can I expect my cat to live?

Unfortunately aged kidneys do not recover. However, we can slow the progress of the disease and improve your cat’s well being with treatment and regular checkups. We check  phosphorous and potassium levels to see if your cat requires supplements and check for urinary tract infections at least every 3 months. This should give your cat a good stretch of high quality, active life.

 

 

Cat fights

Cats typically have a hate-hate relationship with any strange cat in their presence, yard, or environment. When new cats meet, they fluff up, spit, hiss – more like scream! – and the fur soon goes flying. While the brawl may only last a few seconds, that’s enough time for a few diseases to jump bodies.

Feline leukemia (FeLV), feline immunodeficiency virus or cat AIDS (FIV), infectious peritonitis (FIP), or nasty bacterial infections are transmitted from cat to cat in saliva.

Outside cats, particularly unneutered males, love to fight. Most times they will end up with a nasty abscess.

What exactly is an abscess? It’s basically a pocket of pus under the skin. It makes a cat very ill because of the bacteria and toxins it releases into the bloodstream. He is feverish, goes off his food, hides and sleeps a lot.

Treatment for abscesses involves a general anaesthesia, clipping and cleaning the skin, lancing the abscess and flushing all the pus out, placing a drain to allow any new pus to empty, antibiotics and pain relief. Some cats are so sick they need hospitalisation and intravenous fluids for a night or two.

How do we avoid all this??

Desex your cat if he is still entire. Keep him indoors, particularly in the evenings and at night when the brawling usually happens.

Keep other cats off your property. A dog on patrol will soon despatch an intruder. Otherwise keep an eye out for a few evenings and frighten strays off with a loud noise.

Catch the infection as soon as possible. If your cat has been in a fight bring him immediately for an antibiotic shot to discourage the abscess from forming.

Vaccinate your cat against FIV, Feline AIDS. There are three shots in the initial course. A booster at the annual checkup and vaccine review prevents the virus gaining a toe hold.

 

Lilies poison cats

All species of lilies are toxic to cats. Indoor cats with little choice in plant munching material are most at risk as they will try any cut flower that comes into the house.

Any part of the plant – flowers, leaves or stems – is dangerous. Even lily pollen licked off the coat destroys cats’ kidney tubules.

Lilies proven to poison cats include: Easter Lily (Lilium longiflorum), Tiger Lily ( Lilium tigrinum), Day Lily (Lilium hemerocallus), Asian lily (Lily asiatic spp.) and(Lilium rubrum).

If you see your cat with lily on her coat, in her mouth or in her vomit don’t wait for signs of poisoning. The sooner we get it out of her system and start treatment to protect the kidneys the greater her chance of survival.

Affected cats vomit and are depressed within hours of ingesting lily. Some then seem to recover before starting to show signs of severe kidney failure a day or so later. Others continue vomiting, go off their food and get more and more depressed.

If emptying the stomach and medications to prevent absorption of the toxin are effective, the chance of recovery is excellent.

If your cat absorbs enough toxin to cause damage to her kidneys then her outlook is very poor. It is essential to seek emergency care immediately after ingestion of the lily plant.

Rats and rabbits are not affected by lilies but there could be a risk to dogs.

 

Worms in cats

Tapeworms and roundworms are the most common intestinal parasites of cats.

Tapeworms are long flat worms composed of many individual segments which look like wriggling grains of rice in cat faeces.

Round worms are much shorter and rounder and produce microscopic eggs. Hookworm and whipworm are rarer but cause anæmia, loss of protein and gastrointestinal upsets.

Cats are infested with the flea tapeworm Dipylidium caninum by eating fleas carrying the tapeworm during grooming.  The tapeworm mature in cats and pass segments in the faeces which flea larvae ingest.

Cats are infested with the tapeworm Taenia taeniaformis when they eat infected rodents. Infestation with this worm is more common in hunting cats.

Roundworms, Toxocara cati and Toxascaris leonine, are common in young cats and kittens. Cats are infested with roundworm by ingesting worm eggs passed in cat faeces or by eating animals such as mice, which are infested with roundworm.

Most kittens are infested with Toxocara cati through their mother’s milk.

Toxocara cati can infest children if they ingest eggs attached to kitten hair or dirty litter trains.  The eggs hatch to larvae which migrate through the body and may cause damage. To prevent ingestion deworm kittens and cats as advised below, and dispose of litter and disinfect the tray with boiling water at least weekly.

Good quality broad spectrum wormers like Milbemax, Profender spot on and Drontal for cats are effective against all gastrointestinal worms.

Our recommended deworming protocol:

  • Kittens from 4 to 12 weeks of age
    • Treat every two weeks with Milbemax, Profender or Drontal for cats
  • Young cats 3-6 months
    • Treat monthly with Milbemax, Profender or Drontal for cats
  • Cats 6 months of age and older
    • Treat every three months with Milbemax, Profender or Drontal for cats

Feline Leukaemia

Feline leukaemia virus (FeLV) is an important viral infection of young cats in multi-cat households. Over the last few years infection has become less common.

What diseases are associated with FeLV?

FeLV infection suppresses the immune system making the cat susceptible to secondary infections and chronic diseases that would not affect a normal healthy cat. These include mouth ulceration, cat flu, and fungal infections.

Cancers of the white blood cells and solid tumours such as lymphoma cause 10-25% of FeLV deaths.

Anaemia and other blood cell abnormalities are very common in FeLV infected cats. Other FeLV-related diseases include abortion, fading kittens, diarrhoea, neurological or nervous system signs, and immune-mediated disease.

Around 80-90% of persistently FeLV-infected cats will die within 3.5 years of diagnosis.

How is the virus transmitted?

The virus is transmitted by direct contact between cats during grooming or sharing of litter trays and food bowls over a long period of time.

The virus is fragile and does not survive for long in the environment.

An infected queen passes the virus on to all her kittens if she carries them to term. However, this is uncommon as infection with FeLV usually causes infertility or abortion.

What happens when a cat is exposed to FeLV?

Not all cats exposed to FeLV go on to develop FeLV-related diseases. Most cats eliminate the virus from the body, although some remain latently infected for a few months before they  conquer the virus completely.

In cat colonies where the virus is endemic only 30% of cats are persistently infected with FeLV and go on to develop FeLV-related disease. These cats are responsible for the transmission of FeLV to other cats.

How do we diagnose FeLV?

A test at the surgery detects FeLV virus in the blood of a persistently infected cat.

A negative result is always negative. Your vet will assess the predictive value of a positive result by taking your cat’s environment, housemates and outside access into account.

Cats in the process of eliminating the virus will test positive. A second test performed 8-12 weeks after the first test confirms persistent infection.

Is there any treatment for FeLV infection?

There is no treatment that eliminates the virus from the body.

Infected cats should be desexed and confined indoors to prevent exposure to infectious agents and other cats.

Because FeLV-infected cats are more susceptible to disease, vaccination for the common viruses that cause cat flu and enteritis is very important.

We treat secondary infections and other problems like mouth ulcers as they arise.

Most FeLV-infected cats eventually die of their infection or we elect to euthanase them if they are suffering.

Can we prevent infection?

If possible do not house your cat with a known infected cat. Any new cat to the household should test negative for FeLV.

If all the cats in the house are FeLV negative, confinement indoors will prevent casual exposure to wandering cats with the virus.

Breeders may prevent FeLV infection by blood testing all cats and isolating infected individuals.

Vaccination of cats in contact with other infected or potentially infected cats is advisable. As with other vaccines, an initial course of two injections is required, and annual boosters are necessary to maintain immunity.

 

Feline FIV and AIDS

FIV (Feline Immunodeficiency Virus) is prevalent in Australian cats but testing positive for FIV is not the same as having feline AIDS.

Feline AIDS describes the terminal stages of disease which may not occur for many years – or at all! A positive FIV test means that your cat has been infected by the virus.

 

Are my family at risk?

 

No. Although FIV belongs to the same family of viruses as HIV in people, it only infects cats. There is no risk of cross infection of either virus between species.

 

Are other cats in the household likely to be infected?

 

The virus is shed in the saliva of infected cats and spread by biting. Cats with a history of cat bite abscesses are more likely to test positive for FIV.

Spread between cats in a household is unlikely unless they fight. Normal social interactions such as grooming rarely transmit FIV.

The best way to minimise the chances of FIV infection is to confine uninfected cats indoors away from aggressive cats.

 

How is FIV diagnosed?

FIV is diagnosed with a blood test at the surgery which detects an immune response (antibodies) to the virus. If this test is positive your cat is infected.

Kittens with immunity passed on from their mother may test positive until 4 months of age. If a young kitten tests positive we retest them at six months of age.

Will my cat recover?

Once a cat is infected with the virus it remains infected for the rest of its life but not all infected cats  become ill.

 

What diseases does FIV cause?

Like HIV, FIV suppresses the body’s defences so that the cat is vulnerable to diseases it would normally  defeat. The cat is vulnerable to chronic or recurrent infections that fail to respond to regular treatment.

These include:

  1. Inflammation of the mouth and tongue leading to appetite loss, drooling and mouth pain
  2. Weight loss
  3. Poor appetite
  4. Fever
  5. Signs of brain dysfunction such as aggression, unequal pupils, convulsions and behavioural changes
  6. Swollen lymph glands
  7. Unusual infections like toxoplasmosis, cryptococcosis, chronic flu, pneumonia, skin disease
  8. Tumours especially those of the lymph system

The non specific signs of weight loss, poor appetite and fever occur in many diseases of cats and are usually unrelated to FIV. Cats with FIV are more likely to suffer from these signs and diseases more often and  be less able to throw them off even with treatment.

FIV positive cats have a shorter life expectancy on average than FIV negative cats.

Is there any treatment?

 

Secondary infections with bacteria or fungi are treated with antibiotics and anti-fungals but no specific treatment for the virus is available. Trials with anti-HIV drugs such as AZT have reduced mouth inflammation in affected cats but the cost and availability of AZT makes its use in general practice difficult at present.

Anti-inflammatory treatment reduces mouth inflammation and peps up the appetite in many cats.

 

Should I have my cat euthanased?

 

Certainly not on the basis of a positive FIV test!  Like humans with HIV, cats with FIV appear healthy and happy for a long time before getting sick.

On the other hand if your cat has succumbed to multiple infections, is no longer responsive to treatment or is suffering from a chronically painful mouth then euthanasia is the kindest solution.

 

How can I help my cat?

 

Confinement indoors of an FIV positive cat  reduces the risk of infection with other agents. It also reduces the risk of transmission of the virus to other cats.

A good quality, highly palatable diet as well as worming every 3 months and at least annual health checks will enhance the disease free period.

Infections require prompt and aggressive treatment.

 

How do we prevent FIV infection?

 

Desexing and confinement indoors, especially at night, reduces fighting and therefore the risk of infection. We recommend vaccination with FIV vaccine for all cats with access to the outdoors. Cats older than 6 months of age are tested for FIV before the first vaccination. A series of three primary vaccinations is given 2-4 weeks apart and then a booster is given annually.

 

Hairballs?

Hairballs are overrated as a problem in cats.  A true hairball is hair wrapped in saliva and requires no treatment.  Hairballs almost never cause illness in pet cats.

On the other hand we should see your cat if she vomits frequently – whatever the vomitus is! If she is turning her nose up at her dinner or hiding then we should see her as soon as possible. Normal cats eat several times a day so even a single day of poor appetite is significant.

If she vomits a lot but doesn’t feel poorly she may still have a problem. Some cats are very sensitive to specific proteins like chicken, beef or lamb. A change to a diet free of the common proteins that cause hypersensitivity or to one that is specially treated to reduce reactions often helps these cats.

Often the only sign of inflammatory bowel disease or cancers of the bowel is frequent vomiting. Eventually affected cats lose weight or stop eating, but this is when the disease is well advanced. If a cat does not respond within a few weeks to a change of diet as mentioned above then we investigate more closely.

Hyperthyroidism

Hyperthyroidism is a common disorder of older cats.  An overactive thyroid gland produces and secretes too much thyroid hormone putting pressure on all body organs. Any sex or breed of cat can be affected.

The signs of hyperthyroidism include:

  • Weight loss
  • Increased appetite
  • Hyperactivity and restlessness
  • Increased heart rate, associated with irregularities in rhythm, murmurs and high blood pressure
  • Increased frequency of defecation with occasional accidents inside
  • Increased thirst and urination
  • Occasional vomiting
  • Panting
  • Matted, greasy and unkempt coat
  • Enlarged thyroid glands on the neck

If we suspect that your cat has hyperthyroidism we send blood for measurement of the thyroid hormone, T4. We also check for secondary liver, heart or kidney problems.

We usually treat hyperthyroidism with tablets or drops and recommend radioactive iodine therapy once your cat’s system has settled down.

  1. 1. Anti-thyroid drug therapy

Anti-thyroid drugs interfere with the production and secretion of thyroid hormone. They control rather than cure the condition.

Carbimazole (brand name Neo Mercazole) tablets are given twice daily. We see mild and often transient side effects in a few cats on this medication. These include poor appetite, vomiting and lethargy. More serious side effects including a fall in the white blood cell count, clotting problems, or liver disorders occasionally result. If we find any serious side effects after 2 weeks of medication we switch to another treatment.

Many owners prefer methimazole as a gel applied to the inside of the ear or made up into a palatable liquid.

Hyperthyroidism often covers up kidney troubles in cats.  If your cat seems to be drinking or urinating a lot more on medication then alert us as soon as possible.

  1. 2. Radioactive iodine therapy

If kidney problems are not uncovered by anti-thyroid therapy then we suggest radioactive iodine, a more permanent cure for hyperthyroidism. Radioactive iodine only destroys the affected thyroid tissue and leaves adjacent normal tissue, including the parathyroid glands, untouched.

We refer you to a special facility at Canberra Veterinary Hospital for radioactive iodine therapy. Treated cats are kept in hospital for a week after the treatment until they are no longer a radiation risk to people.

Radioactive iodine treatment is curative and has no serious side-effects. Depending on the age of the cat at diagnosis the cost of treatment is similar to long term anti-thyroid drugs or surgery.

It is the only effective treatment for thyroid adenocarcinoma, the cancer that causes 1 to 2% of feline hyperthyroid cases.

  1. 3. Surgical thyroidectomy

Removal of the thyroid glands provides an immediate cure but has some nasty potential side effects so we don’t often recommend it.

Old kidneys need more water

Oscar

Cats with kidney disease all need more fluids. If your cat has kidney problems or is just getting on a bit you should encourage more water consumption.

Provide a choice of water bowls: many cats favour metal or porcelain bowls while others prefer plastic bowls filled to the brim. Put one in the laundry and another on the porch. Fill some from the kitchen tap and others from the laundry tap. Your cat is a connoiseur of water and will taste the difference!

Water fountains are popular with some pusses. If your cat runs when she hears water running into the basin then she will like a water fountain. We have Drinkwell water fountains for sale at Hall Vet Surgery.

A little chicken, beef or fish stock added to the water tempts some cats to the bowl.

Increase the amount of wet food you offer your cat. You can also add more water to cans, sachets or fresh meat.

If your cat is a dry food fiend then soak some of the dry food in water. Even if he doesn’t accept it the first time you offer it he might the fourth or fifth time.

Have you found any tricks to increase cats’ fluid consumption? Hit the comment button below and tell us all!