Tag Archives: Anxiety Medication

Helping ‘Zeke’ to Chill – Why some anxious dogs need medication

Zeke’s owner Ella had lot of experience raising other dogs, including her chilled female Pug X, Morgan. But puppy Zeke (also a Pug X) was different. He seemed anxious and aroused on his walks, barking and lunging at unfamiliar people, dogs, cars and bikes with hackles raised. Ella was especially concerned when Zeke reacted  aggressively towards children as her own baby was on the way. It was a fiasco getting through the gate into the dog park and he would visibly shake with dilated pupils during car trips. Games were no fun as Zeke’s mouthy play had escalated to biting hard and holding on!

Ella had taken Zeke to puppy preschool and tried adolescent obedience classes with an experienced trainer, however Zeke could only focus enough to learn when taken off to a far corner away from the other dogs. So with one month to go before Ella’s baby was due, Ella and Jordan brought 9 month old Zeke for a veterinary behaviour consultation.

Zeke’s issues stemmed from an underlying anxiety, a common cause of behavioural problems associated with a physical anomaly in brain chemistry.  This is a medical disorder caused in part by his genetic makeup as well as previous experiences.

Anxious animals, like anxious people have trouble coping with even small changes in routine. They also react fearfully towards ‘normal’ things in their world because they perceive these as threats. Unfamiliar dogs, people, kids and car trips were so distressing for Zeke that he would go into a fight or flight response in an attempt to escape or avert the trigger for his fear.

Anxious dogs have trouble learning new things because they are focused on what they perceive as life threatening matters around them. Their fear brain is in overdrive and hijacks their ability to think. This is where medication can help turn things around. Just as we might treat a diabetic dog with insulin to manage their illness, medication is helpful to manage anxiety.

Zeke was prescribed anti-anxiety medication to normalise his brain chemistry so that he could better cope with perceived stressors in his day to day life and learn calmer responses.

Is medication enough to cure anxious behaviour?

In most cases anxiety can be managed but not cured and medication alone is not enough. Anxious behaviours including fear aggression, separation anxiety, noise sensitivity and compulsive disorders require a three pronged treatment plan supervised by a behaviour veterinarian for best results. These animals do not grow out of their anxiety and without treatment they can get worse with time. Life continues to present opportunities for the dog to rehearse and reinforce the fear response.

During the behaviour consultation, and detailed in the report that followed, we formulate a plan with Ella and Jordan:

  • To modify Zeke’s exposure to the environmental triggers in order to reduce opportunities for him to practice the anxious behaviours.
  • To practice simple training tools that reinforce calm behaviour.
  • To use anti-anxiety medication and calming pheromones to set Zeke’s brain up for success
What is the effect of the medication?

Anti-anxiety medication is not sedation. The medication prescribed for Zeke increases serotonin levels in the brain and helps these nerve pathways to function more normally over time. This helps him to be less reactive and improves his ability to learn that calm behaviour is rewarding. By dampening the reactivity, Zeke can better learn positive associations to things that previously scared him. Ella compared Zeke with her’ normal’ dog, Morgan who rested most of the time between periods of exercise. Zeke remained bright and alert, however the medication helped him to be less restless and reactive.

When does the medication start to work?

There are two main categories of anti-anxiety medication – long term daily medication to reduce general anxiety levels and short term medication given as needed to manage particular stressful events.

The long term medications prescribed for Zeke take 6-8 weeks to become properly effective although further improvement can be expected up to 12 months after beginning. As they take effect, Ella has noticed Zeke is better able to learn and she finds it easier to teach him to be calm. She knows to take baby steps and choose times to reward calm behaviour where there are few distractions.

Event medications work quickly, often within an hour of dosing and can help greatly for potentially stressful events like thunderstorms, vet visits or being left alone. Zeke found a recent storms scary and coped best when Ella let him snuggle into bed with her. This is a situation where an event medication may help to calm Zeke and block his memory of the storm so that future events are less scary.

How long will my pet be on medication?

We recommend that Zeke continues the medication for at least 12 months so that it can take full effect and give Ella enough time with Zeke to shape calm habits. There is no quick fix for changing anxiety based behaviours. Behaviour modification is different from obedience training. Effective behaviour change is about changing the underlying emotional response to the situations that previously triggered fear. This takes time.

The length of time on medication differs with each individual case and follow up is important to reassess each individual’s needs. The severity of the problem, the desired outcome, the commitment to the behaviour modification program, the family and environmental situation and the pet’s reaction to the medication all influence the length of treatment.

In some cases, the pet’s behaviour problem is managed so successfully that we can wean them off the medication. In other cases, both pet and owner have a much better quality of life if the pet remains on medication long term.

Is medication safe for my pet?

All medications have the potential for side effects and these differ with each one. Generally speaking, side effects of the anti-anxiety medication that we prescribed for Zeke are rare or mild. Personality changes are not expected. The most common side effects associated with the baseline anti-anxiety medications, are a transient gastrointestinal upset or reduced appetite and mild sedation that resolves during the first two weeks. Behaviour medications are excreted through the liver and kidneys so we check with a blood test before starting and then annually to ensure these organs remain healthy.

What about pheromones?

Dog appeasement pheromone is a synthetically derived chemical identical to that produced by female dogs during lactation, which acts to calm and reassure their pups. It has been proven to help reduce anxiety in both puppies and adult dogs during stressful situations. It is available as a diffuser, spray or collar. Ella set up the diffuser to help Zeke relax indoors.


Some positives for Zeke, Ella and Jordan since starting him on medication to reduce anxiety: 

  • Medication has helped us teach him to be calm which means he can be included in baby time. He can interact with the baby instead of being separated.


  • Zeke can now watch TV with us at night without seeking our attention by mouthing at us


  • We had tried to implement things such as sitting behind a toddler gate when visitors arrived but before the medication he would try to jump the gate and we had no success. He still has room for improvement but now we can get him to sit and wait for small periods of time. 


  • When walking Zeke on lead it was almost impossible to get him to walk past houses with dogs barking in the windows or at the gates and now we can hold his attention long enough to walk past these houses with little disruption.